The applications of Gentian violet

Gentian violet also known as Crystal violet, . it is methyl violet The name is due to its color, it like that of the petals of a gentian flower
BUT……….not made from gentians or from violets
When dissolved in water the dye has a blue-violet colour.
Gentian violet’s common side effect is the staining of skin and cloth, but it can easily be washed off skin with a solution of bleach and water.
-It is generally safe for use on children and breastfeeding mothers.
It can be applied to the mouth and lips of premature infants
– gentian violet can be use for thrush on the nipple.
Applications :Gentian violet has antibacterial, antifungal, and anthelmintic properties .

-Tinea; e.g. Athlete’s foot, jock itch, and ringworm

-Candida albicans and related infections; e.g. thrush, yeast infections.

-Mouth ulcers

-Impetigo, used primarily before the advent of antibiotics, but still useful to persons who may be allergic to penicillin, as it cleans the open sores and prevents spread of the contagion.

– It will prevent infection in almost any wound or burn and quickly help the epithelium form a scab. It does not burn when applied and temporary skin discoloration is a minor side effect.

-Marking the skin for surgery preparation and allergy testing .

– Bacteria stained with crystal violet .

– The dye is also used as a histological stain, particularly in Gram’s method for classifying bacteria

Butterfly Rash

Butterfly Rash

 photo sle_zps25657d0a.jpg

 photo SKIN009_zps6c65d79f.jpg


  1.  Describe the clinical finding?
  2. What underlying diseases give rise to this condition?
  3. Name 4 diagnostic criteria for diagnosis of the condition.
  4. Write the modalities of treatment.

Answer Sheet:

  1.  Describe the clinical finding?
    C/F: This is a photograph showing Butterfly Rash,
  2. What underlying diseases give rise to this condition?
    Systemic Lupus Erythematosus (SLE)
  3. Name 4 diagnostic criteria for diagnosis of the condition.
    a. Malar Rash
    b. Discoid Rash
    c. Serositis
    d. Oral ulcer
    e. Arthritis
    f. Photosensitivity
  4. Write the modalities of treatment.
    a. Avoid sun and UV light exposure
    b. Use of high factor sun blocks
    c. Intermittent analgesics.
    d. NSAIDs: In mild disease
    e. Short courses of oral corticosteroid for mild to moderate
    f. For severe : High dose corticosteroid
    g. Other immunosuppressive drugs

Primary Lesions of Skin

Macule: Small spot (Less than 5 mm), different in color from surrounding skin, that is neither elevated nor depressed below the skin surface.

Patch: Large spot (>5mm) different in color from surrounding skin.

Papule: Small (less than 5mm diameter) circumscribed solid elevation on the skin.

Plaque: Large (>5mm) superficial flat lesion, often formed by a confluence of papules

Nodule: Large cirumscribed solid skin elevation .

Pustule: Small circumscribed skin elevation containing purulent material.

Vesicle: Small (<5mm) circumscribed skin blister containing serum.

Bulla: Large(>5mm) vesicle containing free fluid.

Wheal: Irregular elevated edematous skin area, which often changes in size and shape.

Cyst: Enclosed cavity with a membraneous lining which contains liquid or semisolid matter .

Tumor: Large nodule, which may be neoplastic .

Telangiectasia: Dilated superifical blood vessel.

Burrow: A linear or curvilinear papule, caused by a burrowing scabies mite.

Comedone: A plug of keratin and sebum wedged in a dilated pilosebaceous orifice.


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