Define AIDS. Mention opportunistic infection in AIDS.
AIDS (Acquired Immuno Deficiency Syndrome):
It is a syndrome complex, which is caused by human immuno deficiency virus (HIV).
Opportunistic infection in AIDS:
1) M. tuberculosis
2) M. avium intracellulare (MAI)
3) M. kansasii
4) Nocardia asteroids
5) Listeria monocytogenes
1) Cytomegalovirus (CMV)
2) Herpes simplex virus
3) Herpes zoster
4) Hepatitis B virus (HBV)
1) Candida species
2) Cryptococcus neoformans
3) Histoplasma species
1) Pneumocystic carinii
2) Cryptosporidium species
3) Isospora belli
4) Strongyloides stercoralis
5) Sarcocystic species
What are the causes of opportunistic infection in AIDS.
Causes of opportunistic infection in AIDS:
HIV infects CD4 + T-cells. As a result there is loss of T-cell response to form cytotoxic T-cell and proliferation and differentiation of B cell. So both the cell mediated and antibody mediated immunity is lost. For this reason opportunistic pathogens cause severe disease.